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Novel Noninvasive Methods of Intracranial Pressure and Cerebrovascular Autoregulation Assessment: Seeing the Brain Through the Eyes

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Technical Report,01 Jan 2018,31 Dec 2018

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Regents of the University of Michigan Ann Arbor United States

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Traumatic brain injury TBI is a major public health problem in the U.S. and around the world. It plays a major role in approximately 30of injury related civilian deaths in the U.S. and is often referred to as the silent epidemic because of associated complications that go undiagnosed and unnoticed, but might have a lasting effect. Furthermore, the Defense and Veterans Brain Injury Center DVBIC has reported over 34,000 moderate to severe combat-related TBI CRTBI since 2000, making it a major source of mortality and morbidity for the U.S. military between 2000 and 2016. The significance of such numbers and statistics becomes apparent with the militarys increased focus on Prolonged Field Care PFC and prolonged damage control resuscitation pDCR. PFC is defined by Keenan as the field medical care, applied beyond doctrinal planning time-lines by a SOCM Special Operations Combat Medic or higher, in order to decrease patient mortality and morbidity, utilize limited resources, and provide sustained care until the patient arrives at an appropriate level of care. Approximately 20 of individuals with combat-related severe TBI suffer acute neurological deterioration in the first 72 hours following injury, the potential time window of PFC. The austere, resource-constrained combat environment and lack of diagnostic capabilities could lead to delayed recognition of the severity of a TBI or in having rationale treatment end-points, resulting in exacerbated secondary brain damage and increased TBI-related disabilities. This is especially true when TBI-related injuries are combined with other injuries requiring pDCR.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

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