Accession Number:

AD1094136

Title:

Harnessing Neuroplasticity to Promote Rehabilitation: CI Therapy for TBI

Descriptive Note:

Technical Report,30 Sep 2014,29 Sep 2018

Corporate Author:

University of Alabama at Birmingham Birmingham United States

Personal Author(s):

• Taub,Edward
• Uswatte,Gitendra

Report Date:

2018-12-01

Pagination or Media Count:

54.0

Abstract:

This study evaluated Constraint-Induced Movement CI therapy for promoting motor recovery in veterans and civilians with traumatic brain injury TBI. This form of physical rehabilitation has been shown to substantially improve motor function after brain injury not due to trauma and to provoke a widespread neuroplastic response in the brain. This single blind, randomized controlled trial N 40 compared CI therapy for improving use of the more-affected arm in adults with TBI to a holistic fitness program named Lakeshore Enriched Fitness Training LEFT. In addition to assessing changes from pre-treatment in more-affected arm motor function at post-treatment and 1-year afterwards, changes were examined in white matter, grey matter, and functional brain activity. Products at the end of the four years of this blinded study were a manual of procedures, a method for generating synthetic neuroimaging data for the purpose of evaluating the sensitvity of the techniques proposed for quantifying changes in grey matter, and a manuscript on the study protocol.

Descriptors:

• brain injuries
• trauma
• rehabilitation
• UPPER EXTREMITY
• physical therapy
• arms(anatomy)
• adults
• veterans(military personnel
• civilian population
• interventions
• training
• therapeutics
• neuroimaging
• craniocerebral trauma
• motor function impairment

Subject Categories:

• Medicine and Medical Research
• Weapons Effects (Biological)

Distribution Statement:

APPROVED FOR PUBLIC RELEASE