Accession Number:

AD1093648

Title:

Follistatin: A Potential Anabolic Treatment for Re-innervated Muscle

Descriptive Note:

Technical Report,15 Aug 2015,14 Nov 2018

Corporate Author:

Virginia Commonwealth University Richmond United States

Personal Author(s):

Report Date:

2019-02-01

Pagination or Media Count:

34.0

Abstract:

Follistatin is a possible anabolic treatment for denervation atrophy induced muscle weakness following prolonged denervation. Follistatin DNA treatment seemed to have both anabolic and neurotrophic effects when administered after nerve repair following prolonged 6-month temporary denervation. Follistatin protein treatment was not associated with improved recovery though both protein and DNA treatments stimulated regenerative satellite cells. These observations are encouraging and warrant further investigation.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE