Accession Number:

AD1093538

Title:

Development of a Prognostic Marker for Lung Cancer Using Analysis of Tumor Evolution

Descriptive Note:

Technical Report,01 Aug 2017,31 Jul 2018

Corporate Author:

Duke University Durham United States

Personal Author(s):

Report Date:

2018-08-01

Pagination or Media Count:

8.0

Abstract:

The goal of this project is to sequence the exomes of single tumor cells from tumors in order to construct evolutionary trees, the characteristics of which will be used to predict whether a tumor will metastasize or not. Since the last annual report, we continued to collect fresh lung tumor specimens, process them into single cell suspensions, and isolate and amplify DNA for sequencing. Laboratory Corporation of America LabCorp took over the sequencing for this project, and all sequencing is complete. We have received all the data and are in the midst of data processing, mutation analysis, and construction of phylogenetic trees

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE