Accession Number:

AD1092013

Title:

Multispecies, Integrative GWAS for Focal Segmental Glomerulosclerosis

Descriptive Note:

Technical Report,15 Aug 2018,14 Aug 2019

Corporate Author:

Trustees of Columbia University New York United States

Personal Author(s):

Report Date:

2019-09-01

Pagination or Media Count:

17.0

Abstract:

The overall goals of this project are to identify novel susceptibility variants to human nephrotic syndrome caused by focal segmental glomerulosclerosis FSGS and minimal change disease MCD. Using a variety of statistical and genetic approaches, including genome wide association analysis and rare copy number variations CNVs mapping. Data are then integrated with genetic analyses from mouse models from the partnering project. The identification of novel variants will provide insight into some of the genetic mechanisms that underlie FSGS.

Subject Categories:

  • Medicine and Medical Research
  • Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE