Glutamate Neuroexcitotoxicity in GWI
Technical Report,01 Sep 2018,31 Aug 2019
American University Washington United States
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The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness GWI. The rationale for proposed study comes from data in the fibromyalgia field which suggests that reducing the consumption of dietary glutamate can reduce over-excitation in the nervous system, leading to symptom improvement. Since there is almost complete symptom overlap between fibromyalgia and GWI, it is of utmost importance to test this diet as a low-cost treatment option in GWI patients. Thus far, we have enrolled 38 subjects into the study and have 2 more people scheduled for their initial visit this month. Overall, we are still on pace to recruit a total of 40 subjects in the timeline indicated in our SOW.
- Anatomy and Physiology