Accession Number:

AD1089126

Title:

Interactions of Closed Loop Control PEEP oxygenation and Fluid Therapy

Descriptive Note:

Technical Report,21 Mar 2017,20 Sep 2019

Corporate Author:

711 HPW/RHM Wright-Patterson AFB United States

Personal Author(s):

• Kinskey,Michael

Report Date:

2019-09-30

Pagination or Media Count:

25.0

Abstract:

Background Closed loop control mechanical ventilation has been reported to potentially reduce ventilator weaning time, burden on medical caregivers, and improve comfort during mechanical ventilation. However, the influence of closed loop control PEEP adjustment, on fluid requirements in the acute phase and cardiopulmonary dysfunction, remains unknown. The aim of this study was to investigate the impact of closed loop ventilation and PEEPFiO2 on decision support-based fluid resuscitation and respiratory mechanicsgas exchange using a clinically relevant ovine model of burn and smoke inhalation.

Descriptors:

• airway management
• VENTILATION
• decision aids
• resuscitation
• CLOSED LOOP SYSTEMS
• ANIMAL EXPERIMENTATION
• sheep
• burn injuries

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE