Accession Number:

AD1088178

Title:

Scalability and Safety Studies in Clinical-Grade Pluripotent-Derived Myogenic Progenitors for Therapeutic Application in DMD

Descriptive Note:

Technical Report,30 Sep 2018,29 Sep 2019

Corporate Author:

Regents of the University of Minnesota Minneapolis United States

Personal Author(s):

Report Date:

2019-10-01

Pagination or Media Count:

10.0

Abstract:

During the second year of this grant, we finalized optimization of the CD54 MACS-purification protocol in vitro and in vivo validation as well as completed the growth curve studies as well as the in vivo experiments using the optimized media composition. Whole genome sequencing and mapping of integration sites has also been achieved.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE