Using Multimodal Imaging to Examine the Neural Mechanisms of an Integrative Exercise Program for Individuals with Dementia
Technical Report,01 Aug 2018,31 Jul 2019
Northern California Institute for Research and Education San Francisco United States
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The goal of this project is to investigate whether participation in the Preventing Loss of Independence through Exercise PLI program for 4 months will result in neurobiological changes that improve cognitive function, leading to improvements in physical function and quality of life QOL. We will estimate the impact of PLI on brain atrophy rates, Default Mode Network DMN functional connectivity, and cerebral perfusion and determine if improvements in cognition, function, and QOL are associated with changes in brain volume, DMN functional connectivity, and cerebral perfusion in individuals who participated in PLI.
- Anatomy and Physiology
- Medicine and Medical Research