A Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS
[Technical Report, Annual Report]
UNIVERSITY OF CALIFORNIA
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We hypothesize that specific human GI microbiota can alter the balance of inflammatory and regulatory immune cell populations thus leading to disease in genetically susceptible hosts. Furthermore, we hypothesize that gut microbiota from subjects with RMS and PPMS is fundamentally different and can elicit distinguishable effects when transferred into susceptible animal models of the disease.
- Medicine and Medical Research
- Anatomy and Physiology