Meditation for Posttraumatic Stress Disorder: A Systematic Review
[Technical Report, Final Report]
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Posttraumatic stress disorder PTSD is a debilitating condition that emerges after exposure to a traumatic event. Meditation may provide a safe, self-administered, and inexpensive complement to first-line treatments for PTSD. This systematic review synthesized evidence on meditation interventions for the treatment of PTSD PROSPERO 2015 CRD42015025782. We searched eight electronic databases from inception to November 2015 and bibliographies of existing systematic reviews to identify English-language randomized controlled trials RCTs evaluating the efficacy and safety of meditation interventions in patients with PTSD. Two independent reviewers screened identified literature using predetermined eligibility criteria, abstracted study-level information, and assessed study quality. Meta-analyses used the Hartung-Knapp-Sidik-Jonkman method for random-effects models. The quality of evidence was assessed using the GRADE approach. The primary outcome was PTSD symptom severity, and other outcomes included depression, anxiety, quality of life, functional status, and adverse events.