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The Effect of Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation on Visual Performance: A Systematic Review

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Technical Report

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U.S. Army Aeromedical Research Laboratory FORT RUCKER United States

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Objective To determine whether nutritional supplementation with lutein L, zeaxanthin Z, andor mesozeaxanthin MZ results in improved human visual performance. Method A systematic literature search was performed on the effects of L, Z, andor MZ supplementation on human visual performance. The databases which were queried were Pubmed and ScienceDirect. Results A totalof 19 studies were identified and analyzed. Combined analysis of all these studies revealed that 1 there were no safety concerns from L, Z, and MZ supplementation, and 2 with supplementation there was either improvement of visual performance or there was no change in visual performance. There were no studies in which visual performance decreased with supplementation. Several promising trends materialized from these studies contrast sensitivity, glare disability, photostress recovery, critical flicker fusion frequency, and photophobia all showed general improvement with supplementation. Visual acuity and color vision, on the other hand, showed no improvement, or had inconclusive results.

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  • Anatomy and Physiology

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