Accession Number:

AD1069453

Title:

The Development of Nitroxide-Containing Anti-Biofilm Agents

Descriptive Note:

Technical Report,15 Sep 2016,14 Sep 2018

Corporate Author:

QUEENSLAND UNIVERSITY OF TECHNOLOGY BRISBANE Australia

Personal Author(s):

• Fairfull-Smith,Kathryn

Report Date:

2019-02-05

Pagination or Media Count:

11.0

Abstract:

The goal of the project was to develop novel nitroxide-based anti-biofilm agents by incorporating nitroxides into the structures of antibiotics and biocides and which can then be attached to polymer scaffolds using various tethering approaches. The Fluoroquinolone-nitroxide hybrid compounds were prepared and tested for their anti-biofilm properties as well as their use as fluorescent probes. This grant award also had a collaboration with researchers from the Air Force Research Laboratory. The PI has had 2 peer reviewed papers, and 6 conference presentations and 2 manuscripts submitted as a direct result of the grant.

Descriptors:

• Coatings
• Biofuels
• anti bacterial agents
• chemical synthesis
• OXIDES
• FILMS
• MICROORGANISMS

Subject Categories:

• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE