Accession Number:

AD1067472

Title:

In Vitro Dermal Corrosion Proficiency Demonstration, April 2018-September 2018

Descriptive Note:

[Technical Report, Technical Report]

Corporate Author:

Army Public Health Center

Personal Author(s):

Report Date:

2019-02-08

Pagination or Media Count:

25

Abstract:

Prior to routine use of any of the four validated in vitro dermal corrosion test methods specified in the OECD guideline, technical proficiency must be demonstrated using the twelve Proficiency Substances listed in the OECD guideline. This study was conducted as a proficiency demonstration. Proficiency substances were tested using the EPI-SCT-200 assay. All assay acceptance criteria were met and 100 of the proficiency substances were correctly classified, therefore the performing lab is technically proficient and EPI-SCT-200 may be routinely used for in vitro prediction of skin corrosion.

Subject Categories:

  • Anatomy and Physiology
  • Toxicology
  • Biochemistry

Distribution Statement:

[A, Approved For Public Release]