Department of Defense End-of-Season Influenza Vaccine Effectiveness Estimates for the 2017-2018 Season
Journal Article - Open Access,01 Jan 2017,31 Dec 2018
NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA SAN DIEGO United States
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The Department of Defense DoD generates influenza vaccine effectiveness VE estimates each season. The Armed Forces Health Surveillance Branch Air Force AFHSB-AF satellite, Naval Health Research Center Operational Infectious Disease Directorate at the Naval Health Research Center NHRC-OID, and the Armed Forces Health Surveillance Branch AFHSB all conduct influenza surveillance and perform test-negative case-control analyses to estimate seasonal influenza VE for DoD populations. The midseason estimates contribute to the aggregate data utilized by the Food and Drug Administrations Vaccine and Related Biological Products Advisory Committee to select the composition of the influenza vaccine for the next influenza season. The full season data provide DoD with direct estimates for force health protection decisions. The 20172018 DoD influenza season was predominated by influenza AH3N2 with varying levels of adjusted overall VE estimates. AFHSB-AF satellites VE for dependents was moderate at 49 95 confidence interval CI 4255 for all strains. NHRC-OIDs VE among dependents was moderate-high at 63 95 CI 5073 for all strains. AFHSB service member VE was low at 18 95 CI 430. These estimates highlight the need for continued influenza surveillance and VE estimate calculations each season among the different DoD populations as circulating strains and VE may change annually.
- Medicine and Medical Research
- Military Forces and Organizations