Accession Number:

AD1064781

Title:

Understanding the Bioelectric Aspects of Cytoskeletal Dynamics

Descriptive Note:

Technical Report,01 Aug 2015,31 Jul 2018

Corporate Author:

CHICAGO UNIV IL CHICAGO United States

Personal Author(s):

Report Date:

2017-10-28

Pagination or Media Count:

11.0

Abstract:

In the third year of the project, my lab developed a set of matrices to quantify and differentiate the capacitive, Faradaic, and thermal outputs from 30 different Si materials in saline, with the objective of gaining a fundamental understanding of subcellular modulations. We proved light-controlled non-genetic modulations of intracellular calcium dynamics, cytoskeleton-based transport and structures, and cellular excitability. We for the first time discovered the correlation between intracellular transport and intracellular bioelectric activities. During the entire project, we have published several high profile papers, including one on Nature Materials, one Nature Nanotechnology, one Nature Biomedical Engineering.

Subject Categories:

  • Electricity and Magnetism

Distribution Statement:

APPROVED FOR PUBLIC RELEASE