Accession Number:



Comparison of Bladder-Directed and Pelvic Floor Therapy in Women With Interstitial Cystitis/Bladder Pain Syndrome

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Technical Report,01 Sep 2017,31 Aug 2018

Corporate Author:

William Beaumont Hospital Inc Royal Oak United States

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Interstitial cystitisbladder pain syndrome ICBPS is a debilitating constellation of symptoms including urinary urgency, frequency, and pain related to the bladder, which predominantly affects women. Although symptoms appear to be bladder related, there has been little solid evidence linking ICBPS with a dysfunctional bladder epithelium unless ulcers are present. There is growing evidence that the bladder may be an innocent bystander in a more diffuse syndrome with a complex interplay of various systemsfactors. It is our objective to assess the role of the pelvic floor muscles as a major contributor to pelvic pain and voiding dysfunction in adult women with ICBPS symptoms. During Year 2, our primary focus was on study recruitment and enrollment. Due to the national shortage of one of the medications that are used for bladder instillations bladder focused therapy, we only enrolled 1 of 128 total women 64 in each treatment arm in the first project year. In August 2017 we obtained a limited supply of the medication, and study recruitment and enrollment resumed. In Year 2, recruitment activities have been expanded to increase enrollment. Identification of enrollment barriers and possible resolutions are ongoing. Although our targeted enrollment goals are not met, enrollment has been growing steadily.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology

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