Accession Number:

AD1062024

Title:

Colorimetric Biosensor: Crosslinker Variations

Descriptive Note:

Technical Report,01 Jan 2012,20 Sep 2018

Corporate Author:

Center for Bio/Molecular Science & Engineering, NAVAL RESEARCH LAB WASHINGTON United States

Personal Author(s):

• White,Brandy J.
• Taitt,Chris R.
• Archibong,Edikan
• Leska,Iwona A.

Report Date:

2018-10-09

Pagination or Media Count:

45.0

Abstract:

This report is related to an effort that seeks to develop autonomous sensors for environmental monitoring of changes in bacterial populations. The approach uses porphyrin modified antimicrobial peptides to produce colorimetric signatures, enabling the use of devices originally developed for chemical sensing applications. Here, we describe initial work focused on development of the covalent porphyrin-peptide constructs and the evaluation of those materials in the presence and absence of bacterial targets in aqueous solution.

Descriptors:

• PORPHYRINS
• biomedical engineering
• spectra
• amino acids
• anti infective agents
• detectors
• target recognition
• detection
• PORPHYRINS

Subject Categories:

• Pharmacology
• Organic Chemistry
• Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE