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Vibratory Stimuli, A Novel Rehabilitation Method for Preventing Post - Traumatic Knee Osteoarthritis

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Technical Report,01 Aug 2017,31 Jul 2018

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North Carolina at Chapel Hill Chapel Hill United States

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The purpose of this study is to determine and compare the acute effects of whole body vibration and local muscle vibration on quadriceps function, proprioception, and gait biomechanics in individuals with anterior cruciate ligament reconstruction. We hypothesize that both forms of vibration will equally enhance quadriceps function, proprioception, and gait biomechanics in manners that would potentially reduce the risk of developing knee osteoarthritis. While the specific aims will not be realized and cannot be analyzed until the studys completion due to the single-blind randomized controlled trial design, Years 1, 2, and 3 of the project were highly successful regarding progress toward the study aims. The primary goal for Year 3 was to recruit and enroll the final cohort of 15 subjects and complete data analysis. September 25, 2018 will mark the 3-year anniversary of HRPO approval and initiation of research activities in earnest. The proposed sample included 75 individuals with anterior cruciate ligament reconstruction. To date we have enrolled 65 subjects who have completed all testing and 2 who arecurrently participating, have scheduled 1 potential subject for the initial screening session, and have recruited 5 potential subjects who are in the scheduling cue for the screening session. These data are in agreement with the target enrollment rateof 6-8 subjects per quarter specified in the SOW. We have been granted a no-cost extension for the project, and anticipate complete subject enrollment in the next two months. There have been no unanticipated problems, and data collection has proceeded as planned.

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  • Medicine and Medical Research

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