Accession Number:

AD1058234

Title:

Nanoparticles as Antimicrobial Surface Modifiers

Descriptive Note:

[Technical Report, Final Report]

Corporate Author:

Columbia University

Personal Author(s):

• Campos, Luis M.
• Killops, Kathryn

Report Date:

2016-06-17

Pagination or Media Count:

8

Abstract:

Antimicrobial coatings are important for healthcare, specifically focusing on wound healing and preventive measures of infection and harm from biological agents. Synthetic materials that are capable of serving as antimicrobial coatings have received much attention for their ability to be synthesized in large scale, as opposed to naturally occurring and synthetic polypeptides, that must be extracted and purified from biological sources or require extensive synthetic steps. To overcome this challenge we propose to develop a platform of polyelectrolyte nanoparticles based on a new class of cationic monomers to serve as antimicrobialbiocide coatings. These materials have the added benefit of being applicable as smart coatings, thermal photonic lattices, anti-reflective coatings for solar panels, and for various interfacial modifiers. We will focus on systems that are modular in order impact other areas of materials research in future studies.

Descriptors:

• chemistry
• copolymers
• therapy
• biomedical and dental materials
• biomolecules
• block copolymers
• electron microscopy
• materials
• organic chemistry
• polymer chemistry
• polymeric films
• polymers
• anti-infective agents
• gene therapy
• nanoparticles
• nucleic acids
• department of defense
• engineering
• gel electrophoresis
• light scattering

Subject Categories:

• Miscellaneous Materials
• Chemical, Biological and Radiological Warfare

Distribution Statement:

[A, Approved For Public Release]