Accession Number:

AD1057984

Title:

Commentary: What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence

Descriptive Note:

Journal Article - Open Access

Corporate Author:

Universit Libre de Bruxelles (ULB) Gosselies Belgium

Report Date:

2017-02-14

Pagination or Media Count:

3.0

Abstract:

In a recent paper published in Frontiers in Microbiology, Ramisetty et al. 2016 questioned the mainstream model regarding bacterial persistence proposed by the group of K. Gerdes Maisonneuve et al., 2011, 2013. Persistence is an important phenomenon thought to contribute to infectious diseases chronicity and antibiotic resistance selection Michiels et al., 2016. This reversible and low frequency phenotypic switch allows bacteria to enter a particular physiological state in which they can sustain the presence of a given antibiotic Kaldalu et al., 2016Wood, 2016.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE