Determination of the Chronic Mammalian Toxicological Effects of RDX. Twenty-Four Month Chronic Toxicity/Carcinogenicity Study of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) in the B6C3F1 Hybrid Mouse. Phase 4, Volume 3, Appendix 11: Final Pathology Report
IIT RESEARCH INST CHICAGO IL CHICAGO United States
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In accordance with the amended experimental protocol gross and histopathologic examinations were performed on organs and tissues of B6C3F1 hybrid mice for IITRI Project L6121, Study Number 7. The mice were divided into five groups, each consisting of 85 males and 85 females. Four of the five groups were each treated with different doses of HEXAHYDRO-1,3,5-TRINITRO-1,3 and TRIAZINE RDX for twenty-four months. The mice of the fifth group did not receive RDX and did serve as a control group.