Accession Number:

AD1051165

Title:

Non-Uniformly Sampled MR Correlated Spectroscopic Imaging in Breast Cancer and Nonlinear Reconstruction

Descriptive Note:

Technical Report,30 Sep 2016,29 Sep 2017

Corporate Author:

University of California, Los Angeles Los Angeles United States

Personal Author(s):

Report Date:

2017-10-01

Pagination or Media Count:

9.0

Abstract:

Magnetic Resonance Imaging MRI is an excellent anatomical tool to image tissue non-invasively. Dynamic contrast enhanced MRI DCE-MRI has excellent sensitivity but with varying specificity. MR Spectroscopy MRS enables biochemical characterization non-invasively of metabolites. Three major hypotheses are 1 Accelerated 5-dimensional 5Decho-planar imaging based correlated spectroscopic imaging EP-COSI acquisition produces multi-slice based multi-voxel two-dimensional 2D MRS in a clinically feasible time. 2 Incorporating non-uniform under sampling NUS for spectralspatial sampling into the 5D EP-COSI data acquisition and the group sparsity GS-based reconstruction will reduce the total acquisition time by at least a factor of 12.

Subject Categories:

  • Medicine and Medical Research
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE