The goal of the Mississippi prostate cancer HBCU Undergraduate Research Training Program was to promote interest in careers in PCa research and care among undergraduate students from Tougaloo College TC and Jackson State University JSU at the University of Mississippi Medical Center UMMC-Cancer Institute CI. During the execution of this award, 14 undergraduate scholars from TC and JSU, gained experience in performing PCa research at UMMC-CI. Scholars of this program have been accepted into graduate studies programs focused in cancer biology 4 others joined other higher education in Health Sciences related programs 3 some have been hired as employees in careers related to health care 3 and some of them are currently pursuing graduation 4. Fifty one 51 meeting presentations in the poster or oral format included work related to internships during the current report period trainees received numerous 18 awards manuscripts published 1 and 4 in preparation include trainees as coauthors and 3 PCa Research Mini Symposiums have been organized. Research projects are leading to development of novel effective treatments and addressing mechanisms of resistance for men with high-risk or metastatic PCa. Likewise, these projects will eventually help distinguishing aggressive from indolent disease in men newly diagnosed with PCa. This Program has provided minority scholars with interests in PCa research and healthcare.