A Novel Vector Control Measure to Combat the Spread of Artemisinin Resistance in the Greater Mekong Subregion
Technical Report,30 Sep 2016,29 Sep 2017
Mahidol University Nakhon Pathom Thailand
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Survey for study site selection was conducted in 4 provinces, in Thailand Ranong, Surat Thani, Ratchaburi and Kanchanaburi. Blood was collected by finger pricking from population at selected sites. Blood samples from people with malaria symptom were examined for malaria by RDT on site. Malaria examination by quantitative PCR or qMal was performed for all samples. More than 5,100 blood samples were collected, among this 346 of them had symptom during the survey. There were 35 samples positive for malaria by qMal and 4 samples were positive by RDT. Preliminary entomology surveys were conducted during reporting period for planning purpose for the vector survey which will be started in FY2018. Database management system has been established for the study including, but not limited to, blood survey forms, GIS mapping of sites, etc. Laboratory protocols have been validated and applied for blood survey and will be used for vector survey. Protocols for longitudinal blood survey and vector survey have been prepared and submitted for HRPO pre-review. Sites in Surat Thani will selected for the further longitudinal study based on recent analysis. Longitudinal surveillance will be conducted in FY2018 prior to ivermectin mass drug administration to ensure that there will be enough population with malaria for randomized controlled trial.
- Medicine and Medical Research