Accession Number:

AD1048405

Title:

Metformin Therapy for Fanconis Anemia

Descriptive Note:

Technical Report,01 Aug 2016,31 Jul 2017

Corporate Author:

Oregon Health and Science University Portland United States

Personal Author(s):

• Grompe, Markus

Report Date:

2017-08-01

Pagination or Media Count:

7.0

Abstract:

This award pertains to the treatment of the inherited bone marrow failure syndrome Fanconis Anemia. Specifically, the commonly used diabetes drug metformin will be tested by itself and in combination with the current standard of care, anabolic steroids.

Descriptors:

• anemias
• genetic disorders
• drugs
• androgens
• deoxyribonucleic acids

Subject Categories:

• Medicine and Medical Research
• Genetic Engineering and Molecular Biology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE