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Evaluation of the Physiological Challenges in Extreme Environments: Implications for Enhanced Training, Operational Performance and Sex-Specific Responses

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Technical Report,30 Sep 2016,29 Sep 2017

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University of Montana Missoula United States

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The specific aim of the second segment of this project series was to determine the impacts of environmental conditions on specific markers of exercise training response andor acclimation. Untrained males n36 served as study participants and were stratified across three training environments 1 control 20C, 30 RH, 2 heat 33C, 30 RH, or 3 cold 7C, 30 RH environments. Daily training was prescribed for a period of 14 days. Following a controlled diet and exercise plan the day before and after overnight fast participants reported to the laboratory in the early morning hours. A muscle biopsy was obtained from the vastus lateralis randomized, counter-balanced leg before starting exercise Pre days 1 and 15. Participants then exercised for 60 minutes at 60 of maximal aerobic capacity in one of the above-described environments. At the conclusion of the exercise trial, participants recovered seated rest, under normal laboratory conditions for four hours before a final muscle biopsy was taken days 1 and 15. The additional four hours was necessary for the genes of interest to peak following exercise as previously described. Data was analyzed using a mixed design ANOVA with repeated measures between the training groups and across time, two-way 2 x 3 ANOVA time x trial. A probability of type I error of less than 5 was considered significant p 0.05. At the time of this report, only a portion of the data has been analyzed. However, we have completed all study participant training and testing for this phase of the study males.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology

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