Accession Number:

AD1047329

Title:

Long Term Follow up of the Delayed Effects of Acute Radiation Exposure in Primates

Descriptive Note:

Technical Report,30 Sep 2016,29 Sep 2017

Corporate Author:

Wake Forest University Health Sciences Winston Salem United States

Personal Author(s):

Report Date:

2017-10-01

Pagination or Media Count:

137.0

Abstract:

The overarching goal of this program is to explore our recent clinically relevant observations of DEARE in a unique cohort ofnon-human primates NHP, termed the Radiation Survivor Cohort RSC. This work consists of 4 projects 1. Studies of type 2diabetes mellitusT2DM 2. Radiation-induced heart disease RIHD 3. Chronic immune impairment with restriction of the antigenic responserepertoire and 4. Genomic and transcriptomic studies of the molecular pathogenesis of T2DM, RIHD, and immune impairmentin the context of DEARE.

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Distribution Statement:

APPROVED FOR PUBLIC RELEASE