Long Term Follow up of the Delayed Effects of Acute Radiation Exposure in Primates
Technical Report,30 Sep 2016,29 Sep 2017
Wake Forest University Health Sciences Winston Salem United States
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The overarching goal of this program is to explore our recent clinically relevant observations of DEARE in a unique cohort ofnon-human primates NHP, termed the Radiation Survivor Cohort RSC. This work consists of 4 projects 1. Studies of type 2diabetes mellitusT2DM 2. Radiation-induced heart disease RIHD 3. Chronic immune impairment with restriction of the antigenic responserepertoire and 4. Genomic and transcriptomic studies of the molecular pathogenesis of T2DM, RIHD, and immune impairmentin the context of DEARE.