Accession Number:

AD1046205

Title:

Mechanisms Underlying Stress Fracture and the Influence of Sex and Race/Ethnicity

Descriptive Note:

Technical Report,30 Sep 2016,29 Sep 2017

Corporate Author:

Massachusetts General Hospital Boston United States

Personal Author(s):

• Bouxsein, Mary
• Popp,Kristin
• Caksa,Signe
• Rudolph,Sara

Report Date:

2017-10-01

Pagination or Media Count:

10.0

Abstract:

This cross-sectional clinical study aims to examine potential mechanisms contributing to stress fracture risk. In particular, in Study 1, we will perform advanced skeletal imaging along with gait-assessments in subjects with history of a single vs multiple vs no prior stress fractures. In addition, in Aim 2, we will perform advanced imaging to delineate variation in skeletal features according to sex and raceethnic-origin that may contribute or protect from stress fracture. To date, we have enrolled 21 subjects in Study 1 with an additional 9 subjects scheduled for their visit. Enrollment for both Aims is ongoing. Skeletal assessments are behind schedule due to the delay in installation of the second generation high-resolution peripheral quantitative computed tomography device at MGH. As studies are ongoing, we have not performed any data analyses.

Descriptors:

• bone fractures
• ETHNIC GROUPS
• SEX
• BIOMECHANICS
• risk

Subject Categories:

• Medicine and Medical Research
• Anatomy and Physiology
• Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE