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Why Does Acute Postwhiplash Injury Pain Transform into Chronic Pain Multimodal Assessment of Risk Factors and Predictors of Pain Chronification

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Technical Report,25 Sep 2016,24 Sep 2017

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Technion Research and Development Foundation Haifa Israel

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The study aims to explore why acute pain turns, in some patients, into chronic pain, and to develop tools for prediction of this transition. We use mild traumatic brain injury as our work model, to study which of the factors measured in the acute whiplash pain phase, influence the chronification of head and neck pain in these patients. Our objective is to construct a specific and sensitive tool, based on a broad assessment of pain modulation parameters obtained during acute pain, which allows understanding of the underlying mechanisms relevant for prediction of the transition to the chronic phase. This is a prospective, non-intervening, longitudinal study. Acute whiplash patients are recruited when visiting the Rambam Health Care Campus ER immediately after the injury. Psychophysical, neurophysiological, psychological, imaging and genetic data are being collected within 72 hours. Patients are being followed up for one year.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology

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