High-Fidelity Design of Multimodal Restorative Interventions in Gulf War Illness
Technical Report,30 Sep 2016,29 Sep 2017
NOVA Southeastern University Fort Lauderdale United States
Pagination or Media Count:
Our objective is to further refine models of immune and endocrine regulatory dysfunction developed under W81XWH-10-1-0774 Broderick PI by improving fidelity of the timescale and drug action thereby translating previously idealized treatments into optimally beneficial low-risk drug re-purposing strategies that are immediately deployable as short exposure courses in phase-I clinical trials. With collaborating PI Dr. Whitley CSU, we continue to make substantive progress towards project goals during this reporting period, specifically in the development of i a formal algorithmic approach for direct integration of data with the contextual logic, ii an algorithmic approach for model discovery and validation, and iii redefinition of the treatment paradigm to focus on destabilization of illness and remission reachability.
- Medicine and Medical Research
- Theoretical Mathematics