Accession Number:

AD1044365

Title:

Follistatin: A Potential Anabolic Treatment for Re-Innervated Muscle

Descriptive Note:

Technical Report,15 Aug 2016,14 Aug 2017

Corporate Author:

Virginia Commonwealth University Richmond United States

Personal Author(s):

• Isaacs, Jonathan

Report Date:

2017-09-01

Pagination or Media Count:

25.0

Abstract:

Follistatin is a possible anabolic treatment for denervation atrophy induced muscle weakness following prolonged denervation. Adenovirus delivery of Recombinant FS-288 DNA isoform does not induce hypertrophy in normal rodent gastrocnemius muscle. The efficacy of Adenoassociated virus delivery of FS-288 DNA or direct delivery of recombinant FS-288 protein is currently not known.

Descriptors:

• ATROPHY
• nerves
• muscles
• wounds and injuries
• proteins
• deoxyribonucleic acids
• drugs

Subject Categories:

• Biochemistry
• Anatomy and Physiology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE