Accession Number:

AD1043107

Title:

Spinal Cord Swelling and Alterations in Hydrostatic Pressure After Acute Injury

Descriptive Note:

Technical Report,30 Sep 2016,29 Sep 2017

Corporate Author:

University of British Columbia, ICORD Vancouver Canada

Personal Author(s):

• Kwon, Brian K.

Report Date:

2017-10-01

Pagination or Media Count:

76.0

Abstract:

In year 3 of our grant, we conducted a series of experiments evaluating the effects of duraplasty onintraparenchymal spinal cord oxygenation, blood flow, and pressure, downstream metabolic response, behavioral recovery as well as histological changes. We ended up repeating our 12-week behavioral recovery study because an earlier study that we performed showed a tremendous and frankly, amazing improvement in locomotor function in the duraplasty-treated animals.

Descriptors:

• SPINAL INJURIES
• spinal cord
• inflammation
• Hydrostatic Pressure
• CEREBRAL EDEMA
• LOCOMOTION
• physiological effects

Subject Categories:

Distribution Statement:

APPROVED FOR PUBLIC RELEASE