Accession Number:

AD1043041

Title:

Jet Fuel Exacerbated Noise-Induced Hearing Loss: Focus on Prediction of Central Auditory Processing Dysfunction

Descriptive Note:

Technical Report,01 Oct 2015,01 Mar 2017

Corporate Author:

Henry M. Jackson Foundation for the Advancement of Military Medicine Wright-Patterson AFB United States

Personal Author(s):

• Sterner,Teresa R.
• Robinson,Peter J.
• Hack,C. E.
• Qi,Lining
• Narayanan,Latha
• Law,Sarah T.
• Covington,Tammie R.
• Merrill,Elaine A.
• Grobe,Nadja
• Brown,Dominique N.
• Mattie,David R.

Report Date:

2017-09-01

Pagination or Media Count:

128.0

Abstract:

Multiple laboratory rat studies link JP-8 jet fuel exposure to enhanced noise induced hearing loss NIHL. Further, JP-8 jet fuel exposure, with and without noise, has been found to result in central auditory system dysfunctions in rats. Aircraft pilots, technicians and maintenance crews have frequently shown increased hearing loss. The overall objective of this project was to develop a multi-scale model, together with relevant supporting experimental data, to describe jet fuel exacerbated noise induced hearing loss.

Descriptors:

• pharmacokinetics
• hearing loss
• central nervous system
• stress (physiology)
• ear
• brain
• neural pathways
• synapses
• neurons
• JET ENGINE FUELS
• EXPOSURE (PHYSIOLOGY)
• AIRCRAFT NOISE

Subject Categories:

• Stress Physiology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE