Accession Number:

AD1041628

Title:

Safety Parameter Considerations of Anodal Transcranial Direct Current Stimulation in Rats

Descriptive Note:

Technical Report,01 Oct 2015,01 Sep 2017

Corporate Author:

Infoscitex Corporation Dayton United States

Personal Author(s):

• McKinley,R. A.
• Jankord,Ryan
• Jackson,Mark P.
• Truong,Dennis
• Bikson,Marom
• Brownlow,Milene L.
• Wagner,Jessica A.

Report Date:

2017-10-01

Pagination or Media Count:

28.0

Abstract:

A commonly referenced transcranial Direct Current Stimulation tDCS safety threshold derives from tDCS lesion studies in the rat and relies on electrode current density and related electrode charge density to support clinical guidelines. Concerns about the role of polarity e.g., anodal tDCS, sub-lesion threshold injury e.g., neuroinflammatory processes, and role of electrode montage across rodent and human studies support further investigation into animal models of tDCS safety.

Descriptors:

• direct current
• current density
• brain
• electrodes
• statistical analysis
• computational modeling

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE