Safety Parameter Considerations of Anodal Transcranial Direct Current Stimulation in Rats
Technical Report,01 Oct 2015,01 Sep 2017
Infoscitex Corporation Dayton United States
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A commonly referenced transcranial Direct Current Stimulation tDCS safety threshold derives from tDCS lesion studies in the rat and relies on electrode current density and related electrode charge density to support clinical guidelines. Concerns about the role of polarity e.g., anodal tDCS, sub-lesion threshold injury e.g., neuroinflammatory processes, and role of electrode montage across rodent and human studies support further investigation into animal models of tDCS safety.
- Medicine and Medical Research