Accession Number:

AD1039647

Title:

CDCA7L and Mechanisms of Increased Male Bias in Glioma

Descriptive Note:

Technical Report,15 Apr 2016,14 Apr 2017

Corporate Author:

The Geneva Foundation Tacoma United States

Personal Author(s):

Report Date:

2017-05-01

Pagination or Media Count:

8.0

Abstract:

We are proposing to study CDCA7L in an NF1 mutant model of astrocytoma and glioblastoma and in neurotransmitter levels in NF1 mutant brains, comparing males and females. The results of his work can be used to develop additional hypotheses on whether a yin-yang relationship exists in males and females between risk for brain cancer and risk for depression, or other earning and social dysfunctions. Developing new treatments for gliomas and learningsocial dysfunction through a better understanding of the basic biology will benefit both male and female NF1 patients in the long term.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE