Accession Number:

AD1039219

Title:

Center for Engineered Biomedical Devices

Descriptive Note:

Technical Report,12 Sep 2011,11 Mar 2013

Corporate Author:

University Of South Dakota Vermillion United States

Personal Author(s):

• Engebretson,Daniel S.

Report Date:

2013-04-01

Pagination or Media Count:

43.0

Abstract:

BACKGROUND Intervertebral disc IVD degeneration is a major source of lower back pain. Current treatment strategies aim to alleviate the associated symptoms and not on restoring the biological function of the intervertebral disc. PURPOSE The objective of this study is to construct an injectable scaffold in vitro as a therapeutic delivery system to improve the mechanical properties of the nucleus pulposus NP of IVD to withstand physiologic loading.

Descriptors:

• pain
• SPINAL COLUMN
• confocal microscopy
• cartilage
• polysaccharides
• tissue engineering
• modulus of elasticity
• calcium compounds
• azo compounds
• therapeutics
• biomedical engineering
• arthritis
• BIOTECHNOLOGY

Subject Categories:

• Anatomy and Physiology
• Biomedical Instrumentation and Bioengineering

Distribution Statement:

APPROVED FOR PUBLIC RELEASE