Accession Number:



Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers with and without PTSD

Descriptive Note:

Technical Report,15 Sep 2013,14 Sep 2014

Corporate Author:

Seattle Institute for Biomedical and Clinical Research Seattle United States

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This project is a 12-week randomized controlled trial RCT of prazosin for AUD in 200 OIFOEF soldiers both withand without comorbid PTSD enrolled in the Alcohol and Substance Abuse Program ASAP at Madigan HealthCare SystemJoint Base Lewis McChord. The aims of this trial are 1 to determine prazosins efficacy for AUD inOIFOEF soldiers participating in outpatient AUD treatment and 2 to determine if the presence of PTSD affectsprazosin efficacy for AUD. In the first year of the study, the protocol was extensively review and recently approvedby the VA Puget Sound IRB. This approval was necessary before the Madigan IRB would review the protocol.Madigan IRB has now accepted the studys application and we anticipate their approval by end of November 2013this would allow an early December 2013 start of participant randomization.

Subject Categories:

  • Psychology

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