Metabolomic Profiling of Prostate Cancer Progression During Active Surveillance
Technical Report,30 Sep 2015,29 Sep 2016
Johns Hopkins School of Medicine Baltimore United States
Pagination or Media Count:
This report covers the fourth year of this project. At the conclusion of the original period of performance a no cost extension NCE was requested to allowsamples to be analyzed by our industry collaborator, Metabolon, Inc. This request was delayed while issues raised by the Office of Research ProtectionHuman Research Protection Office HRPO were addressed, and a protocol specific to this study was submitted to, and approved by the Johns HopkinsSchool of Medicine IRB. With the IRB approval, the issues raised by HRPO were resolved and the study was approved to continue. The NCE was granted,extending the period of performance to October 29, 2017, and authorizing use of previously unspent funds. The samples needed for analysis were identifiedfrom an IRB-approved bank of existing samples from men on active surveillance and the samples have been aliquotted and shipped to Metabolon, Inc. foranalysis. The study is now on track to complete laboratory analyses in April 2017, biostatistical and bioinformatics analyses completed by the end of June2017, and a manuscript submitted by the end of the period of performance in October 2017.
- Medicine and Medical Research