Salivary Proteomic and MicroRNA Biomarkers Development for Lung Cancer Detection
Technical Report,01 Aug 2012,31 Jul 2016
University of California, Los Angeles Los Angeles United States
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This is a lung cancer biomarker development project to test the hypothesis that there are discriminatory biomarkers in saliva that can detect lung cancer with the aim to reduce the number unnecessary diagnostic workups bronchoscopy in patients with suspicious chest symptoms. The major goal is to perform a properly powered biomarker discovery and validation of salivary miRNA and proteomic biomarkers for detection of lung cancer based on PRoBE design principles prospective-specimen-collection and retrospective-blinded-evaluation. The outcome of this project will be a panel of validated non-invasive saliva-based biomarkers for detection of lung cancer.
- Medicine and Medical Research