Accession Number:

AD1036435

Title:

Porcine Collagen Matrix With And Without Enamel Matrix Derivative For The Treatment Of Gingival Recession Defects

Descriptive Note:

Technical Report

Corporate Author:

Uniformed Services University of the Health Sciences Bethesda United States

Personal Author(s):

• Barth,Christopher T.

Report Date:

2016-06-01

Pagination or Media Count:

38.0

Abstract:

The purpose of this study is to compare the effectiveness of a porcine collagen matrix CM, with or without the addition of enamel matrix derivative EMD in the treatment of Miller Class I, II or III recession defects. This will be a prospective, single-blinded, randomized, split-mouth study. One defect will receive CMEMD test, while the other will receive CM control alone. MethodsThe treatment of 30 similarly sized Miller class I, II or III recession defects on single-rooted teeth using coronally advanced flaps with CM EMD or CM alone will be evaluated. The subjects will be in good health, non-smokers, periodontally healthy except for recession, have good oral hygiene and have no contraindications to periodontal surgery. Subjects will have matching recession defects that measure within 1 mm of each other on single-rooted teeth. One defect will be randomly assigned as the test group receiving CM EMD, and the other as the control group receiving only CM. Measurements will be made using a UNC-15 periodontal probe, custom acrylic stent and digital calipers and will include probing depth PD, clinical attachment level CAL, vertical recession RD and width of keratinized tissue KTW. The measurements will be taken at baseline on the day of surgery, and at 3 and 6 months post-surgery.

Descriptors:

• DENISTRY
• teeth
• surgical procedures
• therapeutics
• oral hygiene
• Gingivae
• connective tissue

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE