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Cross-Discipline Bio-Nanostructured Enhanced Photonic Multimode-Sensor Science
Technical Report,15 Mar 2015,14 Jun 2016
UNIVERSIDAD NACIONAL ANDRES BELLO Santiago Chile
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This cross-discipline experimental study aimed to combine soft material science with nanotechnology and multi-physics modeling to produce adaptable bio-nanostructure based on Quantum Dots and Proteins, dropping therefore the cytotoxicity and open new applications in biomedicine, among other areas. We observe from MALDI-TOF analysis two type of proteins in the coating of the Quantum Dots synthetized in bacterias proteins that interact with nucleotides or DNA and chaperone proteins. All these sequences recollected were annotated and analyzed using bioinformatics tools. At the same time, some of the proteins with structural information were model and characterized the residues accessible to the solvent, in order to evaluate a molecular mechanism of the condensation process of the proteins on the surface of the Quantum Dots.
APPROVED FOR PUBLIC RELEASE