Accession Number:

AD1036276

Title:

GCMS/MS Analyses of Biological Samples in Support of Evaluation of Toxicity Associated with Intravenous Exposure to VX Stereoisomers in Guinea Pigs

Descriptive Note:

Technical Report,01 Jan 2016,31 Aug 2016

Corporate Author:

Edgewood Chemical Biological Center Aberdeen Proving Ground United States

Report Date:

2017-07-01

Pagination or Media Count:

60.0

Abstract:

This report documents the results of the gas chromatography tandem mass spectrometry analyses of blood, tissues, and organs heart, lung, liver, kidney, and brain that were obtained from guinea pigs intravenously exposed to various concentrations of O-ethyl S-2-diisopropylaminoethyl methylphosphonothioate VX stereoisomers. The amount of O-ethyl methylphosphonofluoridate VX-G present in these biological samples was quantified using chemical ionization mass spectrometry with isotope dilution.

Subject Categories:

  • Toxicology
  • Biology
  • Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE