Accession Number:



Development of a Novel Segmental Bone Defect Construct

Descriptive Note:

Technical Report,30 Sep 2015,29 Sep 2016

Corporate Author:

University of Missouri System Columbia United States

Personal Author(s):

Report Date:


Pagination or Media Count:



Bone tissue naturally regenerates itself upon injuries like a broken bone. However, when the size of the injury exceeds a threshold value this capability is lost and the injury is referred to as a critical size defect. When this occurs in a war fighter it requires the use of implant technology to either help maintain functionality or induce healing to return the individual to their natural state. However, there are a number of drawbacks to the existing technologies used for injury repair. These include slow healing times, scar tissue formation, and the possibility that the implant will be rejected by the body. Therefore there is interest in the development of new materials to foster the recovery of injured war fighters. The proposed work is focused on the development of such a material and it is targeted towards the segmental bone defect topic area in the FY14 PRMRP.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement: