FastID: Extremely Fast Forensic DNA Comparisons
MIT Lincoln Laboratory Lexington United States
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Rapid analysis of DNA forensic samples can have acritical impact on time sensitive investigations. Analysis of forensic DNA samples by massively parallel sequencing is creating the next gold standard for DNA forensic analysis. This technology enables the expansion of forensic profiles from the current 20 short tandem repeat STR loci to tens of thousands of single nucleotide polymorphism SNP loci. A forensic search scales by the product of the number of loci and the number of profile comparisons. This paper introduces a method FastID to address the need for rapid scalable analysis of DNA forensic samples. FastID can search a profile of 2,500 SNP loci against 20 million profiles in 5.08 seconds using a single computational thread on a laptop Intel i7 4.0 GHz.