Accession Number:

AD1034632

Title:

Beta Blockers for the Prevention of Acute Exacerbations of COPD

Descriptive Note:

Technical Report,30 Sep 2015,29 Sep 2016

Corporate Author:

University of Alabama at Birmingham Birmingham United States

Personal Author(s):

Report Date:

2016-10-01

Pagination or Media Count:

25.0

Abstract:

We are conducting a randomized, placebo-controlled trial to definitively assess the impact of metoprolol succinate on the rate of COPD exacerbations. This is a multicenter, placebo-controlled, double-blind, prospective randomized trial that will enroll 1028 patients with at least moderately severe COPD over a 3-year period. Major activities for this reporting period have centered on contracting, regulatory approvals, training, site initiation and enrollment at clinical sites. Upon execution of contracts and IRB approvals enrollment has been steadily increasing. The monthly enrollment goal is 28.5 across all sites, with each site enrolling an average of 2-3 participants per month. Several sites have met and exceeded this goal in August and September and we expect this trend to continue.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE