Accession Number:

AD1034618

Title:

Super-Resolution Microscopy by Microspheres Embedded in Movable Slabs

Descriptive Note:

Journal Article - Open Access

Corporate Author:

MIT Lincoln Laboratory Lexington United States

Report Date:

2015-09-03

Pagination or Media Count:

3.0

Abstract:

Recent years have witnessed a breakthrough in achieving truly nanoscale resolution by a fluorescent super-resolution microscopy. The label-free microscopy develops more slowly than fluorescent microscopy for two reasons. First, the mechanisms of label-free imaging rely on much more subtle light-scattering processes in nanoplasmonic or biomedical objects that result in lower effective contrast of images. Second, good point-sources in a form of dye-molecules, fluorophores or quantum dots are not readily available in a label-free microscopy that complicates the experimental quantification of resolution.

Subject Categories:

  • Optics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE