Accession Number:

AD1034592

Title:

Skeletal Muscle Hypertrophy and Cardiometabolic Benefits after Spinal Cord Injury

Descriptive Note:

Technical Report,30 Sep 2015,29 Sep 2016

Corporate Author:

McGuire Research Institute, Inc RICHMOND United States

Personal Author(s):

Report Date:

2016-10-01

Pagination or Media Count:

23.0

Abstract:

Spinal cord injury is a devastating medical condition that increases ones risk for reduced aerobic fitness, glucose intolerance and insulin resistance due to increased body fat and relative inactivity. The purpose is to determine the impact of 1212 weeks of NMESFES-LEC on oxygen uptake, insulin sensitivity, glucose uptake, anabolic profileTestosterone and IGF-1, basal metabolic rate BMR. Four participants have completed the trial so far, two from the 1212 weeks NMESFES group and two from the 1212 weeks control FES group. Our preliminary data suggests that 12 weeks of NMES-induced resistance training prior to 12 weeks of FES improves metabolic profile, increases muscle size, and prevents an increase in leg fat mass. The NMESFES group had a 13 increase in basal metabolic rate BMR, while control FES had a 13 decrease in BMR. Both groups experienced increased thigh muscle size with 24 weeks of training 8 for whole thigh and11 for knee extensors. Body composition analysis revealed that NMES FES prevented the 13 increase in leg fat mass experienced by the control FES

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE