Accession Number:



Effectiveness and Patient Acceptability of Stellate Ganglion Block (SGB) for Treatment of Posttraumatic Stress Disorder (PTSD) Symptoms among Active Duty Military Members

Descriptive Note:

Technical Report,01 Mar 2016,28 Feb 2017

Corporate Author:

Research Triangle Institute Research Triangle Park United States

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This study seeks to evaluate the effectiveness and acceptability of stellate ganglion block SGB fortreatment of Posttraumatic Stress Disorder PTSD symptoms. We will conduct two parallel studies arandomized, controlled trial RCT to evaluate the effectiveness of SGB for treating PTSD, and aqualitative study to determine the degree to which the procedure is deemed acceptable by active dutyservice members with PTSD, their spouses, and their providers. A total of 240 individuals will beenrolled for the RCT portion of the study qualitative study participants will be convenience sampledfrom among the RCT participants. For the RCT study, participants will be randomized 21 active SGB tosham across three study sites. Participants will receive the intervention active or sham at weeks 0baseline and 2, and assessments will be conducted at weeks 0, 2, 4, 6, and 8. For the qualitativestudy, individuals enrolled in the RCT will be asked to participate either in a focus group or aninterview with their spouse. In addition, we will conduct focus groups and key informant interviewswith providers those who refer individuals to the study, and those who provide SGB to service members.

Subject Categories:

  • Medicine and Medical Research
  • Psychology

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