Accession Number:

AD1033539

Title:

EMERGE: Engineered Materials that Create Environments for ReGeneration via Electric Field

Descriptive Note:

Technical Report,24 Sep 2015,23 Sep 2016

Corporate Author:

JOHNS HOPKINS UNIV LAUREL MD LAUREL United States

Report Date:

2016-10-01

Pagination or Media Count:

24.0

Abstract:

The report herein describes progress made in the first year of EMERGE Engineered Materials the Create Environments for ReGeneration via Electric Fields. The objective of the project is to develop a next-generation ocular implant material with biomimetic chemistry and nanotopography with unique drug delivery functionality to 1 provide appropriate biochemical and biophysical cues for enhanced cell migration, differentiation and proliferation and 2 deliver wound electric field enhancing pharmaceuticals for enhanced bioelectronics cues. To this end, we are developing a collagen material with tailored nano topography with ability to deliver endogenous wound electric field-enhancing molecules that will encourage and accelerate the wound healing process. We monitor wound electrophysiology as a function of time using a vibrating probe.

Subject Categories:

  • Weapons Effects (Biological)
  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE