EMERGE: Engineered Materials that Create Environments for ReGeneration via Electric Field
Technical Report,24 Sep 2015,23 Sep 2016
JOHNS HOPKINS UNIV LAUREL MD LAUREL United States
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The report herein describes progress made in the first year of EMERGE Engineered Materials the Create Environments for ReGeneration via Electric Fields. The objective of the project is to develop a next-generation ocular implant material with biomimetic chemistry and nanotopography with unique drug delivery functionality to 1 provide appropriate biochemical and biophysical cues for enhanced cell migration, differentiation and proliferation and 2 deliver wound electric field enhancing pharmaceuticals for enhanced bioelectronics cues. To this end, we are developing a collagen material with tailored nano topography with ability to deliver endogenous wound electric field-enhancing molecules that will encourage and accelerate the wound healing process. We monitor wound electrophysiology as a function of time using a vibrating probe.
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